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BMP4 Protein (AA 293-408)

This Recombinant BMP4 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN666737
发货至: 中国

Quick Overview for BMP4 Protein (AA 293-408) (ABIN666737)

抗原

See all BMP4 蛋白
BMP4 (Bone Morphogenetic Protein 4 (BMP4))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 85 %
  • 产品特性

    AA 293-408

    序列

    MSPKHHSQRA RKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR

    产品特性

    BMP- 4, 293-408aa, Human, Recombinant, E.coli

    纯化方法

    > 85% by SDS-PAGE

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    10 mM Sodium Citrate buffer ( pH 3.5) containing 10 % glycerol

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    BMP4 (Bone Morphogenetic Protein 4 (BMP4))

    别名

    BMP-4

    背景

    Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

    分子量

    13.2 kDa (117aa) confirmed by MALDI-TOF

    NCBI登录号

    NP_001193

    途径

    Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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